Federated GWAS workflow
Coordinate quality control, kinship analysis, local regression filtering, and final association analysis across multiple centers.
Private, secure, and reproducible federated GWAS documentation for multi-center studies that need strong data ownership and auditable analysis.
ECC key exchange and pairwise PRG masking for aggregate communication.
Local and global filtering for missingness, MAF, and HWE thresholds.
Distributed PLINK logistic regression with center-level data ownership.
No raw genotype centralization, deterministic anonymization, and masked statistics.
Core documentation paths are split by workflow so setup, examples, and reference material stay easy to scan.
Set up Python, PLINK, Flower, and the required runtime tools.
Run the default tiny correctness experiment from data generation to evaluation.
Browse tiny correctness, performance small, and 1000 Genomes workflows.
Look up Flower run config, YAML schema, output files, and Python entry points.
The documentation follows the repository structure so researchers can move from setup to pipeline internals without switching mental models.
Coordinate quality control, kinship analysis, local regression filtering, and final association analysis across multiple centers.
Use ECC key exchange, pairwise PRG masking, and deterministic ID anonymization to reduce raw data exposure during collaboration.
Run repeatable Flower simulation and local-deployment experiments with scenario-specific configs, logs, and result directories.